Cell lineage of timed cohorts of Tbx6-expressing cells in wild-type and Tbx6 mutant embryos

Tbx6 is a T-box transcription factor with multiple roles in embryonic development as evidenced by dramatic effects on mesoderm cell fate determination, left/right axis determination, and somite segmentation in mutant mice. The expression of Tbx6 is restricted to the primitive streak and presomitic m...

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Bibliographic Details
Main Authors: Daniel Concepcion, Andrew J. Washkowitz, Akiko DeSantis, Phillip Ogea, Jason I. Yang, Nataki C. Douglas, Virginia E. Papaioannou
Format: Article
Language:English
Published: The Company of Biologists 2017-07-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/6/7/1065