Quantifying cerebral contributions to pain beyond nociception

Pain is affected by cerebral processes in addition to afferent nociceptive input. Here the authors develop an fMRI-based signature that predicts pain independent of the intensity of nociceptive signals and mediates the pain-modulating effects of several cognitive interventions.

Bibliographic Details
Main Authors: Choong-Wan Woo, Liane Schmidt, Anjali Krishnan, Marieke Jepma, Mathieu Roy, Martin A. Lindquist, Lauren Y. Atlas, Tor D. Wager
Format: Article
Language:English
Published: Nature Publishing Group 2017-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14211