IGFBP3 methylation is a novel diagnostic and predictive biomarker in colorectal cancer.

Aberrant hypermethylation of cancer-related genes has emerged as a promising strategy for the development of diagnostic, prognostic and predictive biomarkers in human cancer, including colorectal cancer (CRC). The aim of this study was to perform a systematic and comprehensive analysis of a panel of...

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Bibliographic Details
Main Authors: Lucia Perez-Carbonell, Francesc Balaguer, Yuji Toiyama, Cecilia Egoavil, Estefania Rojas, Carla Guarinos, Montserrat Andreu, Xavier Llor, Antoni Castells, Rodrigo Jover, C Richard Boland, Ajay Goel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4134211?pdf=render