Tricin, a methylated cereal flavone, suppresses fat accumulation by downregulating AKT and mTOR in 3T3-L1 preadipocytes

Tricin, a methylated cereal flavone, suppresses fat accumulation by downregulating AKT and mTOR in 3T3-L1 preadipocytes

The anti-adipogenic effect of tricin (5, 7, 4'-trihydroxy-3',5'-dimethoxyflavone), a flavone frequently found in cereal crops, and its underlying molecular mechanism were evaluated in 3T3-L1 preadipocytes. Tricin treatment (5–20 µM) significantly inhibited triacylglycerol (TG) accumul...

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Bibliographic Details
Main Authors: Dabeen Lee, Gwang-Woong Go, Jee-Young Imm
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Journal of Functional Foods
Subjects:
Tricin
Adipogenesis
Molecular mechanism
3T3-L1 adipocytes
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616302377

Internet

http://www.sciencedirect.com/science/article/pii/S1756464616302377

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