Differences in the Thoracic Aorta by Region and Sex in a Murine Model of Marfan Syndrome

Marfan syndrome (MFS) is a hereditary disorder of the connective tissue that causes life-threatening aortic aneurysm, which initiates at the aortic root and can progress into the ascending portion. However, analysis of ascending aorta reactivity in animal models of MFS has remained elusive. Epidemio...

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Bibliographic Details
Main Authors: Francesc Jiménez-Altayó, Anna-Maria Siegert, Fabio Bonorino, Thayna Meirelles, Laura Barberà, Ana P. Dantas, Elisabet Vila, Gustavo Egea
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00933/full