Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE

<p>Abstract</p> <p>Background</p> <p>It has been shown previously that human monocytes fed with haemozoin (HZ) or trophozoite-parasitized RBCs displayed increased matrix metalloproteinase-9 (MMP-9) enzyme activity and protein/mRNA expression and increased TNF production...

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Bibliographic Details
Main Authors: Giribaldi Giuliana, Gallo Valentina, Prato Mauro, Arese Paolo
Format: Article
Language:English
Published: BMC 2008-08-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/7/1/157