DNA Damage and Cell Cycle Arrest Induced by Protoporphyrin IX in Sarcoma 180 Cells

Background: Porphyrin derivatives have been widely used in photodynamic therapy as effective sensitizers. Protoporphyrin IX (PpIX), a well-known hematoporphyrin derivative component, shows great potential to enhance light induced tumor cell damage. However, PpIX alone could also exert anti-tumor eff...

Full description

Bibliographic Details
Main Authors: Qing Li, Xiaobing Wang, Kun Zhang, Xiujuan Li, Quanhong Liu, Pan Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/354479