Strategies to increase the activity of microglia as efficient protectors of the brain against infections

Strategies to increase the activity of microglia as efficient protectors of the brain against infections

In healthy individuals, infections of the CNS are comparatively rare. Based on the ability of microglial cells to phagocytose and kill pathogens and on clinical findings in immunocompromized patients with CNS infections, we hypothesize that an intact microglial function is crucial to protect the bra...

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Bibliographic Details
Main Authors: Roland eNau, Sandra eRibes, Marija eDjukic, Helmut eEiffert
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Bacteria
Blood-Brain Barrier
Microglia
Phagocytosis
Innate immune system
blood-CSF barrier
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00138/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00138/full

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