Gut microbiota and tacrolimus dosing in kidney transplantation.

Gut microbiota and tacrolimus dosing in kidney transplantation.

Tacrolimus dosing to establish therapeutic levels in recipients of organ transplants is a challenging task because of much interpatient and intrapatient variability in drug absorption, metabolism, and disposition. In view of the reported impact of gut microbial species on drug metabolism, we investi...

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Bibliographic Details
Main Authors: John R Lee, Thangamani Muthukumar, Darshana Dadhania, Ying Taur, Robert R Jenq, Nora C Toussaint, Lilan Ling, Eric Pamer, Manikkam Suthanthiran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4376942?pdf=render

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http://europepmc.org/articles/PMC4376942?pdf=render

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