Interferon-y-Induced Growth Inhibition of Neuroblastoma Cells is Independent of Induction of Nitric Oxide Synthase and Indoleamine 2,3-dioxygenase

Interferon-y-Induced Growth Inhibition of Neuroblastoma Cells is Independent of Induction of Nitric Oxide Synthase and Indoleamine 2,3-dioxygenase

We investigated a possible involvement of nitric oxide formed by inducible nitric oxide synthase (iNOS) in the signaling cascade leading to growth inhibition and differentiation in the human neuroblastoma cell line SK-NSII. Treatment of SK-N-SH with interferon-γ (IFN-γ) plus interleukin-lß (IL-lß) l...

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Bibliographic Details
Main Authors: Leitner Stephan, Golderer Georg, Winkler Christiana, Fuchs Dietmar, Werner-Felmayer Gabriele, Werner Ernst R.
Format: Article
Language:English
Published: De Gruyter 2004-08-01
Series:Pteridines
Subjects:
neuroblastoma
nitric oxide synthase
indoleamine 2,3-dioxygenase
interferon-γ
interleukin-1-ß
Online Access:https://doi.org/10.1515/pteridines.2004.15.3.91

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https://doi.org/10.1515/pteridines.2004.15.3.91

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