An impact of nanocrystals on dissolution rate of Lercanidipine: Supersaturation and crystallization by addition of solvent to antisolvent

An impact of nanocrystals on dissolution rate of Lercanidipine: Supersaturation and crystallization by addition of solvent to antisolvent

Abstract Background Nanocrystals of any drug are pure solid drug particles with a mean diameter in nanometer range. Dissolution is a crucial factor for absorption of medicine in case of water-insoluble or poorly soluble drugs. The aim of this study was to develop nanocrystals of a hydrophobic drug,...

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Bibliographic Details
Main Authors: Dolly Tulsibhai Gadhiya, Jayvadan K. Patel, Arti Arjanbhai Bagada
Format: Article
Language:English
Published: SpringerOpen 2021-06-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Lercanidipine
SAS ratio
Nanocrystals
Central composite design
Dissolution enhancement, Nucleation process, Supersaturation
Online Access:https://doi.org/10.1186/s43094-021-00271-x

Internet

https://doi.org/10.1186/s43094-021-00271-x

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