Induction of Hypergammaglobulinemia and Autoantibodies by Salmonella Infection in MyD88-Deficient Mice

Growing evidence indicates a link between persistent infections and the development of autoimmune diseases. For instance, the inability to control Salmonella infection due to defective toll-like receptor (TLR)/myeloid differentiation primary response 88 (MyD88) signaling has linked the development o...

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Bibliographic Details
Main Authors: Jincy M. Issac, Yassir A. Mohamed, Ghada Hassan Bashir, Ashraf Al-Sbiei, Walter Conca, Taj A. Khan, Asif Iqbal, Gabriela Riemekasten, Katja Bieber, Ralf J. Ludwig, Otavio Cabral-Marques, Maria J. Fernandez-Cabezudo, Basel K. al-Ramadi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01384/full