SELECTIVE INHIBITION OF KRAS SIGNALING BY COMBINATION OF LOW DOSE RAPAMYCIN AND PACLITAXEL IN VIVO

SELECTIVE INHIBITION OF KRAS SIGNALING BY COMBINATION OF LOW DOSE RAPAMYCIN AND PACLITAXEL IN VIVO

Background. Therapy with compounds potentially capable to block KRAS oncogene signaling pathway is perspective direction in modern oncopharmacology. The aim of current study was to investigate effects of the combined treatment with rapamycin (RAP) and paclitaxel (PAC) in transgenic zebrafish (Danio...

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Bibliographic Details
Main Authors: M. N. Yurova, D. R. Safina, I. V. Mizgirev
Format: Article
Language:Russian
Published: ABV-press 2018-07-01
Series:Uspehi Molekulârnoj Onkologii
Subjects:
kras
zebrafish
danio rerio
rapamycin
paclitaxel
targeted therapy
mtor
Online Access:https://umo.abvpress.ru/jour/article/view/146

Internet

https://umo.abvpress.ru/jour/article/view/146

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