Comprehensive Analysis of HDAC Family Identifies HDAC1 as a Prognostic and Immune Infiltration Indicator and HDAC1-Related Signature for Prognosis in Glioma

Comprehensive Analysis of HDAC Family Identifies HDAC1 as a Prognostic and Immune Infiltration Indicator and HDAC1-Related Signature for Prognosis in Glioma

Background: The histone deacetylase (HDAC) family limited accessibility to chromatin containing tumor suppressor genes by removing acetyl groups, which was deemed a path for tumorigenesis. Considering glioma remained one of the most common brain cancers with a dichotomy prognosis and limited therapy...

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Bibliographic Details
Main Authors: Yuxiang Fan, Xinyu Peng, Yubo Wang, Baoqin Li, Gang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
glioma
HDAC1
HDAC family
immune infiltration
prognosis
signature
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.720020/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2021.720020/full

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