Study of ICOS gene polymorphisms associations with the risk and clinical course of multiple myeloma

In multiple myeloma (MM) patients, various T-cell abnormalities, such as a marked reduction in the proportions of CD4 and CD8 cells expressing co-stimulatory molecules, signal transduction components, Th1/Th2 imbalance and alterations of regulatory T cells/T helper 17 cells (Treg/Th17 ratio), have b...

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Bibliographic Details
Main Authors: Dariusz Woszczyk, Anna Partyka, Marek Kielbinski, Irena Frydecka, Lidia Karabon
Format: Article
Language:English
Published: Index Copernicus International S.A. 2019-03-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
MM
Online Access:http://phmd.pl/gicid/01.3001.0013.1408