The Role of Endoplasmic Reticulum in the Differential Endurance against Redox Stress in Cortical and Spinal Astrocytes from the Newborn SOD1<sup>G93A</sup> Mouse Model of Amyotrophic Lateral Sclerosis

The Role of Endoplasmic Reticulum in the Differential Endurance against Redox Stress in Cortical and Spinal Astrocytes from the Newborn SOD1<sup>G93A</sup> Mouse Model of Amyotrophic Lateral Sclerosis

Recent studies reported that the uptake of [18F]-fluorodeoxyglucose (FDG) is increased in the spinal cord (SC) and decreased in the motor cortex (MC) of patients with ALS, suggesting that the disease might differently affect the two nervous districts with different time sequence or with different me...

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Bibliographic Details
Main Authors: Cecilia Marini, Vanessa Cossu, Mandeep Kumar, Marco Milanese, Katia Cortese, Silvia Bruno, Grazia Bellese, Sonia Carta, Roberta Arianna Zerbo, Carola Torazza, Matteo Bauckneht, Consuelo Venturi, Stefano Raffa, Anna Maria Orengo, Maria Isabella Donegani, Silvia Chiola, Silvia Ravera, Patrizia Castellani, Silvia Morbelli, Gianmario Sambuceti, Giambattista Bonanno
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antioxidants
Subjects:
Amyotrophic Lateral Sclerosis (ALS)
SOD1<sup>G93A</sup>
astrocytes
endoplasmic reticulum
redox stress
H6PD
Online Access:https://www.mdpi.com/2076-3921/10/9/1392

Internet

https://www.mdpi.com/2076-3921/10/9/1392

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