Disruption of the MyoD/p21 Pathway in Rhabdomyosarcoma
Purpose. Rhabdomyosarcoma (RMS) is an embryonal tumor thought to arise from skeletal muscle cells that fail to differentiate terminally. The majority of RMSs express MyoD, a protein essential to the differentiation of skeletal muscle. It was recently shown that during myogenesis, MyoD activates the...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
1997-01-01
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| Series: | Sarcoma |
| Online Access: | http://dx.doi.org/10.1080/13577149778218 |