Disruption of the MyoD/p21 Pathway in Rhabdomyosarcoma
Purpose. Rhabdomyosarcoma (RMS) is an embryonal tumor thought to arise from skeletal muscle cells that fail to differentiate terminally. The majority of RMSs express MyoD, a protein essential to the differentiation of skeletal muscle. It was recently shown that during myogenesis, MyoD activates the...
Main Authors: | Michael Weintraub, Thea Kalebic, Lee J. Helman, Kishor G. Bhatia |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
1997-01-01
|
Series: | Sarcoma |
Online Access: | http://dx.doi.org/10.1080/13577149778218 |
Similar Items
-
LSD1 Controls Timely MyoD Expression via MyoD Core Enhancer Transcription
by: Isabella Scionti, et al.
Published: (2017-02-01) -
Transcriptional Regulation of the Xenopus MyoD Gene
by: Xiao, Lei
Published: (2003) -
MyoD- and nerve-dependent maintenance of <it>MyoD </it>expression in mature muscle fibres acts through the DRR/PRR element
by: Hughes Simon M, et al.
Published: (2008-01-01) -
Effects of mechanical overload and aging on MyoD and effects of oxandrolone treatment and overload on IGF-1 and MyoD in old rats /
by: Wang, Jianyu
Published: (1998) -
Identifying targets of MyoD in myogenic stem cells
by: Maguire, Richard John
Published: (2009)