GRAPE: a pathway template method to characterize tissue-specific functionality from gene expression profiles

GRAPE: a pathway template method to characterize tissue-specific functionality from gene expression profiles

Abstract Background Personalizing treatment regimes based on gene expression profiles of individual tumors will facilitate management of cancer. Although many methods have been developed to identify pathways perturbed in tumors, the results are often not generalizable across independent datasets due...

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Bibliographic Details
Main Authors: Michael I. Klein, David F. Stern, Hongyu Zhao
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Bioinformatics
Subjects:
Gene expression
Template
Relative expression analysis
Survival analysis
Personalized medicine
Cancer
Online Access:http://link.springer.com/article/10.1186/s12859-017-1711-z

Internet

http://link.springer.com/article/10.1186/s12859-017-1711-z

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