EGCG impedes human Tau aggregation and interacts with Tau

EGCG impedes human Tau aggregation and interacts with Tau

Abstract Tau aggregation and accumulation is a key event in the pathogenesis of Alzheimer’s disease. Inhibition of Tau aggregation is therefore a potential therapeutic strategy to ameliorate the disease. Phytochemicals are being highlighted as potential aggregation inhibitors. Epigallocatechin-3-gal...

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Main Authors: Shweta Kishor Sonawane, Hariharakrishnan Chidambaram, Debjyoti Boral, Nalini Vijay Gorantla, Abhishek Ankur Balmik, Abha Dangi, Sureshkumar Ramasamy, Udaya Kiran Marelli, Subashchandrabose Chinnathambi
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-69429-6

Internet

https://doi.org/10.1038/s41598-020-69429-6

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