Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway.

Current chemotherapeutic agents based on apoptosis induction are lacking in desired efficacy. Therefore, there is continuous effort to bring about new dimension in control and gradual eradication of cancer by means of ever evolving therapeutic strategies. Various forms of PCD are being increasingly...

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Bibliographic Details
Main Authors: Deepak Kumar, Bimolendu Das, Rupashree Sen, Priyanka Kundu, Alak Manna, Avijit Sarkar, Chinmay Chowdhury, Mitali Chatterjee, Padma Das
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4593644?pdf=render