Impaired striatal Akt signaling disrupts dopamine homeostasis and increases feeding.

Impaired striatal Akt signaling disrupts dopamine homeostasis and increases feeding.

<h4>Background</h4>The prevalence of obesity has increased dramatically worldwide. The obesity epidemic begs for novel concepts and therapeutic targets that cohesively address "food-abuse" disorders. We demonstrate a molecular link between impairment of a central kinase (Akt) i...

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Bibliographic Details
Main Authors: Nicole Speed, Christine Saunders, Adeola R Davis, W Anthony Owens, Heinrich J G Matthies, Sanaz Saadat, Jack P Kennedy, Roxanne A Vaughan, Rachael L Neve, Craig W Lindsley, Scott J Russo, Lynette C Daws, Kevin D Niswender, Aurelio Galli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21969871/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21969871/?tool=EBI

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