Identification of New Antifungal Agents Targeting Chitin Synthesis by a Chemical-Genetic Method

Fungal infection is a leading cause of mortality in immunocompromised population; thus, it is urgent to develop new and safe antifungal agents. Different from human cells, fungi have a cell wall, which is composed mainly of polysaccharide glucan and chitin. The unique cell wall structure is an ideal...

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Bibliographic Details
Main Authors: Yan Li, Hongmin Sun, Xiaohong Zhu, Cong Bian, Yanchang Wang, Shuyi Si
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/17/3155