From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases

Genome-wide association studies (GWAS) have successfully mapped thousands of loci associated with complex traits. These associations could reveal the molecular mechanisms altered in common complex diseases and result in the identification of novel drug targets. However, GWAS have also left a number...

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Bibliographic Details
Main Authors: Eddie Cano-Gamez, Gosia Trynka
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00424/full