Cytotoxic Activity of LLO Y406A Is Targeted to the Plasma Membrane of Cancer Urothelial Cells

Identification of novel agents for bladder cancer treatment is highly desirable due to the high incidence of tumor recurrence and the risk of progression to muscle-invasive disease. The key feature of the cholesterol-dependent toxin listeriolysin O mutant (LLO Y406A) is its preferential activity at...

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Bibliographic Details
Main Authors: Nataša Resnik, Larisa Tratnjek, Mateja Erdani Kreft, Matic Kisovec, Saša Aden, Apolonija Bedina Zavec, Gregor Anderluh, Marjetka Podobnik, Peter Veranič
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/7/3305