Selection of a Single Domain Antibody, Specific for an HLA-Bound Epitope of the Mycobacterial Ag85B Antigen
T cells recognizing epitopes on the surface of mycobacteria-infected macrophages can impart protection, but with associated risk for reactivation to lung pathology. We aimed to identify antibodies specific to such epitopes, which carry potentials for development toward novel therapeutic constructs....
Main Authors: | Paola A. Ortega, Mayra Silva-Miranda, Alfredo Torres-Larios, Eduardo Campos-Chávez, Kees C. L. C. M. Franken, Tom H. M. Ottenhoff, Juraj Ivanyi, Clara Espitia |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-10-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2020.577815/full |
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