Peptide Antagonists for P-selectin Discriminate between Sulfatide-Dependent Platelet Aggregation and PSGL-1-Mediated Cell Adhesion

Peptide Antagonists for P-selectin Discriminate between Sulfatide-Dependent Platelet Aggregation and PSGL-1-Mediated Cell Adhesion

Background: Membrane-exposed sulfatides are proposed to contribute to P-selectin-dependent platelet aggregation. Here, we demonstrated that P-selectin-mediated platelet aggregation on a collagen-coated surface under flow indeed depended on sulfatides and that this interaction differed considerably f...

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Bibliographic Details
Main Authors: Suzanne J.A. Korporaal, Tom J.M. Molenaar, Bianca C.H. Lutters, Illiana Meurs, Sandra Drost-Verhoef, Johan Kuiper, Theo J.C. van Berkel, Erik A.L. Biessen
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Journal of Clinical Medicine
Subjects:
antagonists
peptides
platelets
P-selectin
sulfatide
Online Access:https://www.mdpi.com/2077-0383/8/8/1266

Internet

https://www.mdpi.com/2077-0383/8/8/1266

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