Using CRISPR/Cas9 to model human liver disease

Summary: CRISPR/Cas9 gene editing has revolutionised biomedical research. The ease of design has allowed many groups to apply this technology for disease modelling in animals. While the mouse remains the most commonly used organism for embryonic editing, CRISPR is now increasingly performed with hig...

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Bibliographic Details
Main Authors: Michele Alves-Bezerra, Nika Furey, Collin G. Johnson, Karl-Dimiter Bissig
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:JHEP Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555919301077