Simple Algorithms to Calculate Asymptotic Null Distributions of Robust Tests in Case-Control Genetic Association Studies in R

Simple Algorithms to Calculate Asymptotic Null Distributions of Robust Tests in Case-Control Genetic Association Studies in R

The case-control study is an important design for testing association between genetic markers and a disease. The Cochran-Armitage trend test (CATT) is one of the most commonly used statistics for the analysis of case-control genetic association studies. The asymptotically optimal CATT can be used wh...

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Bibliographic Details
Main Authors: Wing Kam Fung, Yong Zang, Gang Zheng
Format: Article
Language:English
Published: Foundation for Open Access Statistics 2010-02-01
Series:Journal of Statistical Software
Subjects:
algorithm
asymptotic distributions
dependence of trend tests
genetic model selection
MAX3
robust tests
Online Access:http://www.jstatsoft.org/v33/i08/paper

Internet

http://www.jstatsoft.org/v33/i08/paper

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