Generation of plasma cells and CD27−IgD− B cells during hantavirus infection is associated with distinct pathological findings

Generation of plasma cells and CD27−IgD− B cells during hantavirus infection is associated with distinct pathological findings

Abstract Objective Human hantavirus infections can cause haemorrhagic fever with renal syndrome (HFRS). The pathogenic mechanisms are not fully understood, nor if they affect the humoral immune system. The objective of this study was to investigate humoral immune responses to hantavirus infection an...

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Bibliographic Details
Main Authors: Priscilla F Kerkman, Andy Dernstedt, Lalitha Tadala, Eva Mittler, Mirjam Dannborg, Christopher Sundling, Kimia T Maleki, Johanna Tauriainen, Anne Tuiskunen‐Bäck, Julia Wigren Byström, Pauline Ocaya, Therese Thunberg, Rohit K Jangra, Gleyder Román‐Sosa, Pablo Guardado‐Calvo, Felix A Rey, Jonas Klingström, Kartik Chandran, Andrea Puhar, Clas Ahlm, Mattias NE Forsell
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
antibodies
atypical B cells
B cells
haemorrhagic fever with renal syndrome
hantavirus
plasmablasts
Online Access:https://doi.org/10.1002/cti2.1313

Internet

https://doi.org/10.1002/cti2.1313

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