Laminopathies: A Pandora's box of heart failure, bradyarrhythmias and sudden death

Introduction: The LMNA gene encodes a group of proteins that have an important structural and functional role in the cell nucleus. Mutations in this gene have been found in 6% of all forms of dilated cardiomyopathy and in up to 33% of those with conduction system disturbances. Aims and Methods: Usin...

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Bibliographic Details
Main Authors: Nuno Cabanelas, Vítor Paulo Martins
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Revista Portuguesa de Cardiologia (English Edition)
Online Access:http://www.sciencedirect.com/science/article/pii/S2174204915000033