Dendritic cell-based vaccination in cancer: therapeutic implications emerging from murine models

Dendritic cell-based vaccination in cancer: therapeutic implications emerging from murine models

Dendritic cells (DCs) play a pivotal role in the orchestration of immune responses, and are thus key targets in cancer vaccine design. Since the 2010 FDA approval of the first cancer DC-based vaccine (Sipuleucel T) there has been a surge of interest in exploiting these cells as a therapeutic option...

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Bibliographic Details
Main Authors: Soledad eMac Keon, Maria Sol eRuiz, Silvina eGazzaniga, Rosa eWainstok
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Immunology
Subjects:
Dendritic Cells
adjuvants
cancer immunotherapy
dendritic cell subsets
dendritic cell maturation
dendritic cell-based vaccines
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00243/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00243/full

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