Anticonvulsant effect of time-restricted feeding in a pilocarpine-induced seizure model: Metabolic and epigenetic implications.

Anticonvulsant effect of time-restricted feeding in a pilocarpine-induced seizure model: Metabolic and epigenetic implications.

A new generation of antiepileptic drugs has emerged; however, one-third of epilepsy patients do not properly respond to pharmacological treatments. The purpose of the present study was to investigate whether time-restricted feeding has an anticonvulsant effect and whether this restrictive diet promo...

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Bibliographic Details
Main Authors: Jorge eLandgrave-Gómez, Octavio Fabián Mercado-Gómez, Mario eVázquez-García, Víctor eRodríguez-Molina, Laura eCórdova-Dávalos, Virginia eArriaga-Ávila, Alfredo eMiranda-Martínez, Rosalinda eGuevara-Guzmán
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
AMP kinase
anticonvulsant
Akt kinase
Beta hydroxybutyrate
histone 3 acetylation
HDACs inhibition
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00007/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00007/full

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