A comprehensive, mechanistically detailed, and executable model of the cell division cycle in Saccharomyces cerevisiae

Whole-cell models hold great promise for fundamental and translational biology, but genome-scale modelling of signalling networks has been a challenge. Here, the authors present a genome-scale, mechanistic and executable model of the network controlling and executing the S. cerevisiae cell cycle.

Bibliographic Details
Main Authors: Ulrike Münzner, Edda Klipp, Marcus Krantz
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08903-w