N-docosahexaenoylethanolamine regulates Hedgehog signaling and promotes growth of cortical axons

Axonogenesis, a process for the establishment of neuron connectivity, is central to brain function. The role of metabolites derived from docosahexaenoic acid (DHA, 22:6n-3) that is specifically enriched in the brain, has not been addressed in axon development. In this study, we tested if synaptamide...

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Bibliographic Details
Main Authors: Giorgi Kharebava, Mohammad A. Rashid, Ji-Won Lee, Sarmila Sarkar, Karl Kevala, Hee-Yong Kim
Format: Article
Published: The Company of Biologists 2015-12-01
Series:Biology Open
Online Access:http://bio.biologists.org/content/4/12/1660