Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life

Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life

The purpose of this study was to investigate whether the anxiolytic effect of cannabidiol (CBD) in humans follows the same pattern of an inverted U-shaped dose-effect curve observed in many animal studies. Sixty healthy subjects of both sexes aged between 18 and 35 years were randomly assigned to fi...

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Bibliographic Details
Main Authors: Antonio W. Zuardi, Natália P. Rodrigues, Angélica L. Silva, Sandra A. Bernardo, Jaime E. C. Hallak, Francisco S. Guimarães, José A. S. Crippa
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Pharmacology
Subjects:
cannabidiol
dose-response
anxiety
healthy volunteers
clonazepam
public speaking
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00259/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00259/full

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