Common Endothelial Nitric Oxide Synthase Single Nucleotide Polymorphisms are not Related With the Risk for Restless Legs Syndrome

Common Endothelial Nitric Oxide Synthase Single Nucleotide Polymorphisms are not Related With the Risk for Restless Legs Syndrome

Because nitric oxide and endothelial dysfunction could play a role in the pathogenesis of idiopathic restless legs syndrome (RLS), as was suggested by some preliminary data, we investigated the possible association between the rs2070744 variants in the endothelial nitric oxide synthase (eNOS or NOS3...

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Bibliographic Details
Main Authors: Félix Javier Jiménez-Jiménez, Blanca G. Agúndez, Javier Gómez-Tabales, Hortensia Alonso-Navarro, Laura Turpín-Fenoll, Jorge Millán-Pascual, Mónica Díez-Fairén, Ignacio Álvarez, Pau Pastor, Marisol Calleja, Rafael García-Ruiz, Santiago Navarro-Muñoz, Marta Recio-Bermejo, José Francisco Plaza-Nieto, Esteban García-Albea, Elena García-Martín, José A. G. Agúndez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
restless legs syndrome
genetics
genetic polymorphisms
nitric oxide
nitric oxide synthase genes
risk factors
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.618989/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.618989/full

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