Mammary epithelial morphogenesis in 3D combinatorial microenvironments

Abstract Human mammary epithelial cells can proliferate and reorganize into polarized multi-cellular constructs in-vitro, thereby functioning as an important model system in recapitulating key steps of in-vivo morphogenesis. Current approaches to constructing such three-dimensional mimics of the in-...

Full description

Bibliographic Details
Main Authors: Raphaelle Luisier, Mehmet Girgin, Matthias P. Lutolf, Adrian Ranga
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78432-w