Oxidative Stress and Genetics in the Pathogenesis of Parkinson's Disease

Parkinson's Disease (PD) is the second most common chronic neurodegenerative disease characterized by the progressive loss of dopamine neurons, leading to rigidity, slowness of movement, rest tremor, gait disturbances, and imbalance. Although there is effective symptomatic treatment for PD, the...

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Bibliographic Details
Main Authors: Yi Zhang, Valina L. Dawson, Ted M. Dawson
Format: Article
Language:English
Published: Elsevier 2000-08-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999610090319X