Compensatory Vasodilator Mechanisms in the Ophthalmic Artery of Endothelial Nitric Oxide Synthase Gene Knockout Mice

Abstract Nitric oxide (NO) generated by endothelial nitric oxide synthase (eNOS) plays an important role in the maintenance of ocular vascular homeostasis. Therefore, perturbations in vascular NO synthesis have been implicated in the pathogenesis of several ocular diseases. We recently reported that...

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Bibliographic Details
Main Authors: Caroline Manicam, Natalja Ginter, Huige Li, Ning Xia, Evgeny Goloborodko, Jenia Kouchek Zadeh, Aytan Musayeva, Norbert Pfeiffer, Adrian Gericke
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07768-7