Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes.

Despite the well-documented effects of plasma lipid lowering regimes halting atherosclerosis lesion development and reducing morbidity and mortality of coronary artery disease and stroke, the transcriptional response in the atherosclerotic lesion mediating these beneficial effects has not yet been c...

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Bibliographic Details
Main Authors: Josefin Skogsberg, Jesper Lundström, Alexander Kovacs, Roland Nilsson, Peri Noori, Shohreh Maleki, Marina Köhler, Anders Hamsten, Jesper Tegnér, Johan Björkegren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2265530?pdf=render