Measurement and correlation study of silymarin solubility in supercritical carbon dioxide with and without a cosolvent using semi-empirical models and back-propagation artificial neural networks

The solubility data of compounds in supercritical fluids and the correlation between the experimental solubility data and predicted solubility data are crucial to the development of supercritical technologies. In the present work, the solubility data of silymarin (SM) in both pure supercritical carb...

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Bibliographic Details
Main Authors: Gang Yang, Zhe Li, Qun Shao, Nianping Feng
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087617300016