Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires.

Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires.

The diversity of T-cell receptors recognizing foreign pathogens is generated through a highly stochastic recombination process, making the independent production of the same sequence rare. Yet unrelated individuals do share receptors, which together constitute a "public" repertoire of abun...

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Bibliographic Details
Main Authors: Mikhail V Pogorelyy, Yuval Elhanati, Quentin Marcou, Anastasiia L Sycheva, Ekaterina A Komech, Vadim I Nazarov, Olga V Britanova, Dmitriy M Chudakov, Ilgar Z Mamedov, Yury B Lebedev, Thierry Mora, Aleksandra M Walczak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5500008?pdf=render

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http://europepmc.org/articles/PMC5500008?pdf=render

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