Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids

Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids

Despite its adverse effects, chemotherapy is generally used for the treatment of colorectal cancer (CRC). Development of supplement preparations targeting cancer stem cells (CSCs) that cause distant metastasis and drug resistance is required. Although curcumin is known to have anti-tumor, hepatoprot...

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Bibliographic Details
Main Authors: Mohamed Elbadawy, Kimika Hayashi, Hiromi Ayame, Yusuke Ishihara, Amira Abugomaa, Makoto Shibutani, Shim-Mo Hayashi, Shoichi Hazama, Hiroko Takenouchi, Masao Nakajima, Ryouichi Tsunedomi, Nobuaki Suzuki, Hiroaki Nagano, Yuta Shinohara, Masahiro Kaneda, Hideyuki Yamawaki, Tatsuya Usui, Kazuaki Sasaki
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Colorectal cancer
Amorphous curcumin
Chemotherapy
Organoid
CSCs
Cell cycle
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222100826X

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http://www.sciencedirect.com/science/article/pii/S075333222100826X

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