Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites

Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites

Correct mitochondrial distribution is critical for satisfying local energy demands and calcium buffering requirements and supporting key cellular processes. The mitochondrially targeted proteins Miro1 and Miro2 are important components of the mitochondrial transport machinery, but their specific rol...

Full description

Bibliographic Details
Main Authors: Guillermo López-Doménech, Nathalie F. Higgs, Victoria Vaccaro, Hana Roš, I. Lorena Arancibia-Cárcamo, Andrew F. MacAskill, Josef T. Kittler
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Cell Reports
Subjects:
dendritic development
mitochondrial transport
neuronal polarity
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716312086

Internet

http://www.sciencedirect.com/science/article/pii/S2211124716312086

Similar Items