Vaccination and Infection of Swine With Salmonella Typhimurium Induces a Systemic and Local Multifunctional CD4+ T-Cell Response

Vaccination and Infection of Swine With Salmonella Typhimurium Induces a Systemic and Local Multifunctional CD4+ T-Cell Response

The gram-negative facultative intracellular bacteria Salmonella Typhimurium (STM) often leads to subclinical infections in pigs, but can also cause severe enterocolitis in this species. Due to its high zoonotic potential, the pathogen is likewise dangerous for humans. Vaccination with a live attenua...

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Bibliographic Details
Main Authors: Selma Schmidt, Elena L. Sassu, Eleni Vatzia, Alix Pierron, Julia Lagler, Kerstin H. Mair, Maria Stadler, Christian Knecht, Joachim Spergser, Marlies Dolezal, Sven Springer, Tobias Theuß, Vicky Fachinger, Andrea Ladinig, Armin Saalmüller, Wilhelm Gerner
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
interferon-γ
interleukin-17A
pig
Salmonella Typhimurium
multifunctional T cells
lamina propria lymphocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.603089/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.603089/full

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