The effect of age on thymic function
Age-related regression of the thymus is associated with a decline in naïve T cell output. This is thought to contribute to the reduction in T cell diversity seen in older individuals and linked with increased susceptibility to infection, autoimmune disease and cancer. Thymic involution is...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2013-10-01
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Series: | Frontiers in Immunology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00316/full |