A new aggressive xenograft model of human colon cancer using cancer-associated fibroblasts

A new aggressive xenograft model of human colon cancer using cancer-associated fibroblasts

Background Colorectal cancer is the second leading cause of cancer death. Almost half of the patients present recurrence within 5 years after the treatment of the primary tumor, the majority, with metastasis. On the other hand, in the search for new animal models that simulate metastatic cancer, it...

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Bibliographic Details
Main Authors: Ester Fernando-Macías, Maria Teresa Fernández-García, Eva García-Pérez, Belén Porrero Guerrero, Camilo López-Arévalo, Raquel Rodríguez-Uría, Sandra Sanz-Navarro, José Fernando Vázquez-Villa, María Carmen Muñíz-Salgueiro, Laura Suárez-Fernández, José A. Galván, Clara Barneo-Caragol, Marcos García-Ocaña, Juan R. de los Toyos, Luis Barneo-Serra
Format: Article
Language:English
Published: PeerJ Inc. 2020-06-01
Series:PeerJ
Subjects:
Xenograft
Animal model
CAFs
Fibroblasts culture
ProColXIα1
Online Access:https://peerj.com/articles/9045.pdf

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https://peerj.com/articles/9045.pdf

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