Probing natural killer cell education by Ly49 receptor expression analysis and computational modelling in single MHC class I mice.

Probing natural killer cell education by Ly49 receptor expression analysis and computational modelling in single MHC class I mice.

Murine natural killer (NK) cells express inhibitory Ly49 receptors for MHC class I molecules, which allows for "missing self" recognition of cells that downregulate MHC class I expression. During murine NK cell development, host MHC class I molecules impose an "educating impact"...

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Bibliographic Details
Main Authors: Sofia Johansson, Mali Salmon-Divon, Maria H Johansson, Yishai Pickman, Petter Brodin, Klas Kärre, Ramit Mehr, Petter Höglund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2699029?pdf=render

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http://europepmc.org/articles/PMC2699029?pdf=render

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