Annexin A2 Regulates AKT Upon H<sub>2</sub>O<sub>2</sub>-Dependent Signaling Activation in Cancer Cells

Annexin A2 Regulates AKT Upon H<sub>2</sub>O<sub>2</sub>-Dependent Signaling Activation in Cancer Cells

Hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) is a main second messenger in oncogenic signaling networks including the Ras and the growth factor receptor pathways. This is achieved predominantly through the oxidation of redox-sensitive cysteine (Cys) residues in proteins res...

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Bibliographic Details
Main Authors: Stéphanie Anais Castaldo, Tom Ajime, Gisela Serrão, Fábio Anastácio, Joana Teixeira Rosa, Carman Anthony Giacomantonio, Alison Howarth, Richard Hill, Patrícia Alexandra Madureira
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
ANXA2
PTEN
PI3K/AKT
PRDX2
H<sub>2</sub>O<sub>2</sub>-dependent signaling
Online Access:https://www.mdpi.com/2072-6694/11/4/492

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https://www.mdpi.com/2072-6694/11/4/492

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